In order to increase the retention time of the drug in the body, Floating Microsphere are used which provide the drug release for more than 12 hours. The main purpose of writing this review on floating drug delivery systems (FDDS) is to correlate and compile the recent literature on the principal mechanism and working of floatation to achieve gastric retention. In this article, Various techniques to design single-unit and multiple-unit floating systems with their classification, formulations and Evaluation aspects such as the Particle size determination and Buoyancy are elaborately discussed. The in vitro techniques and in vivo studies to evaluate the performance and application of floating systems are also mentioned. Floating drug delivery system, are useful for various problems encountered during the development of a pharmaceutical dosage form.
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